Medicinal Use of Marijuana: What School Nurses Need to Know.

 2016 Apr 1. pii: 1942602X16638815. [Epub ahead of print] DeWitt-Parker C1. Author information Abstract The subject of medical marijuana is complex and currently of interest and concern to patients and health care providers. Legislators throughout the United States have passed state-specific laws and regulations that impact medical practice and the use of marijuana as a therapeutic modality. In November […]

Use of cannabinoids in cancer care: palliative care

Curr Oncol. 2016 Mar; 23(2): S33–S36.  Published online 2016 Mar 16. doi:  10.3747/co.23.2962 PMCID: PMC4791145 S.K. Aggarwal, MD PhD* Author information ► Copyright and License information ► Go to: PALLIATIVE CARE IN ONCOLOGY All too often neglected, maximal quality improvement in the setting of life-limiting illness and noxious symptomatology is a worthy medical, public health, and humanitarian goal. The World Health […]

Anticancer mechanisms of cannabinoids.

  Journal List > Curr Oncol > v.23(Suppl 2); 2016 Mar > PMC4791144 Curr Oncol. 2016 Mar; 23(Suppl 2): S23–S32.  Published online 2016 Mar 16. doi:  10.3747/co.23.3080 PMCID: PMC4791144 Anticancer mechanisms of cannabinoids G. Velasco, PhD,*†‡ C. Sánchez, PhD,*§ and  M. Guzmán, PhD*†‖ Author information ► Copyright and License information ► Go to: Abstract In addition to the well-known palliative effects of cannabinoids on some cancer-associated symptoms, a large body […]

In vitro and in vivo efficacy of non-psychoactive cannabidiol in neuroblastoma.

2016 Mar;23(2):S15-22. doi: 10.3747/co.23.2893. Epub 2016 Mar 16. Fisher T1, Golan H2, Schiby G3, PriChen S4, Smoum R5, Moshe I1, Peshes-Yaloz N6, Castiel A6, Waldman D2, Gallily R7, Mechoulam R5, Toren A8. Author information Abstract BACKGROUND: Neuroblastoma (nbl) is one of the most common solid cancers in children. Prognosis in advanced nbl is still poor despite aggressive multimodality therapy. Furthermore, survivors experience severe long-term multi-organ sequelae. […]

Cannabis and cancer: toward a new understanding

Curr Oncol. 2016 Mar; 23(2): S5–S6.  Published online 2016 Mar 16. doi:  10.3747/co.23.3185 PMCID: PMC4791146 Cannabis and cancer: toward a new understanding M.A. Ware, MBBS MSc Author information ► Copyright and License information ► The treatment of cancer, including the disease itself and the symptoms associated with cancer and its therapy, is one of the most important emerging frontiers in cannabinoid […]

Iodine-Promoted Aromatization of p-Menthane-Type Phytocannabinoids.

J Nat Prod. 2017 Dec 14. doi: 10.1021/acs.jnatprod.7b00946. [Epub ahead of print] Pollastro F1, Caprioglio D1, Marotta P1, Moriello AS2, De Petrocellis L2, Taglialatela-Scafati O3, Appendino G1. Author information Abstract Treatment with iodine cleanly converts various p-menthane-type phytocannabinoids and their carboxylated precursors into cannabinol (CBN, 1a). The reaction is superior to previously reported protocols in […]

Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial.

Am J Psychiatry. 2017 Dec 15:appiajp201717030325. doi: 10.1176/appi.ajp.2017.17030325. [Epub ahead of print] McGuire P1, Robson P1, Cubala WJ1, Vasile D1, Morrison PD1, Barron R1, Taylor A1, Wright S1. Author information Abstract OBJECTIVE: Research in both animals and humans indicates that cannabidiol (CBD) has antipsychotic properties. The authors assessed the safety and effectiveness of CBD in […]

Potent anti-inflammatory and pro-resolving effects of anabasum in a human model of self-resolving acute inflammation.

Clin Pharmacol Ther. 2017 Dec 14. doi: 10.1002/cpt.980. [Epub ahead of print] Motwani MP1, Bennett F1, Norris PC2, Maini AA1, George MJ1, Newson J1, Henderson A1, Hobbs AJ3, Tepper M4, White B4, Serhan CN2, MacAllister R1, Gilroy DW1. Author information Abstract Anabasum is a synthetic analogue of Δ8 – tetrahydrocannabinol (THC)-11-oic acid that in pre-clinical […]

Determination of Acid and Neutral Cannabinoids in Extracts of Different Strains of Cannabis sativa Using GC-FID.

Planta Med. 2017 Dec 13. doi: 10.1055/s-0043-124088. [Epub ahead of print] Ibrahim EA1,2, Gul W1,3, Gul SW3, Stamper BJ3,4, Hadad GM2, Abdel Salam RA2, Ibrahim AK5, Ahmed SA5, Chandra S1, Lata H1, Radwan MM1, ElSohly MA1,3,6. Author information Abstract Cannabis (Cannabis sativa L.) is an annual herbaceous plant that belongs to the family Cannabaceae. Trans-Δ9-tetrahydrocannabinol […]

Salivary endocannabinoids and N-acylethanolamines upon mastication of a semisolid food: implications in fat taste, appetite and food liking.

Food Funct. 2017 Dec 13. doi: 10.1039/c7fo01772c. [Epub ahead of print] Mennella I1, Di Monaco R2, Balazy A1, Ferracane R1, Miele NA3, Cavella S2, Vitaglione P1. Author information Abstract This study aimed to evaluate whether salivary endocannabinoid (EC) and N-acylethanolamine (NAE) concentrations upon mastication of a semisolid food were involved in the sensory perception of […]

Increased levels of circulating fatty acids are associated with protective effects against future cardiovascular events in non-diabetics.

J Proteome Res. 2017 Dec 13. doi: 10.1021/acs.jproteome.7b00671. [Epub ahead of print] Kamleh MA, McLeod O, Checa A, Baldassarre D, Veglia F, Gertow K, Humphries SE, Rauramaa R, deFaire U, Smit AJ, Giral P, Kurl S, Mannarino E, Tremoli E, Silveira A, Orvik J, Hamsten A, Wheelock CE. Abstract Cardiovascular disease (CVD) is a major […]

The status of support for cannabis regulation in Uruguay 4 years after reform: Evidence from public opinion surveys.

Drug Alcohol Rev. 2017 Dec 12. doi: 10.1111/dar.12642. [Epub ahead of print] Cruz JM1, Boidi MF2, Queirolo R3. Author information Abstract INTRODUCTION AND AIMS: The objective of this study was to measure the public support for marijuana legalisation in Uruguay, both overall and in its provisions, in nearly 4 years after its implementation. DESIGN AND METHODS: […]

Provider Perspectives on Use of Medical Marijuana in Children With Cancer.

Pediatrics. 2017 Dec 12. pii: e20170559. doi: 10.1542/peds.2017-0559. [Epub ahead of print] Ananth P1, Ma C2,3, Al-Sayegh H2, Kroon L4,5, Klein V4, Wharton C4, Hallez E6, Braun I3,7, Michelson K6,8, Rosenberg AR4,5,9, London W2,3, Wolfe J2,3,7. Author information Abstract BACKGROUND: Although medical marijuana (MM) may have utility in the supportive care of children with serious […]

Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference.

Sci Rep. 2017 Dec 12;7(1):17410. doi: 10.1038/s41598-017-17796-y. Liu QR1,2, Canseco-Alba A3, Zhang HY4, Tagliaferro P3, Chung M3, Dennis E3, Sanabria B3, Schanz N3, Escosteguy-Neto JC3, Ishiguro H5, Lin Z6, Sgro S3, Leonard CM3, Santos-Junior JG7, Gardner EL4, Egan JM8, Lee JW3, Xi ZX4, Onaivi ES9. Author information Abstract Cannabinoid CB2 receptors (CB2Rs) are expressed in […]